Sustiva: Revised Drug-Interaction Information

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Summary: The FDA added new drug-interaction warnings to the prescribing information for Sustiva (efavirenz).


On January 31 the FDA announced that the Sustiva (efavirenz) package insert had been changed “to include drug-drug interaction information regarding coadministration of efavirenz with rifampin, diltiazem, itraconazole, voriconazole, atorvastatin, pravastatin, simvastatin, pimozide and bepridil.”

The complete list of changes is at

And the new version for patients, and also one for physicians, is at (click “Patient Information” to download a PDF file — or click “Full U.S. Prescribing Information” and change the ending of the file name from .pl to .pdf is necessary).


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